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Castleman disease masquerading as a paraganglioma showing uptake on DOTATATE PET
  1. Ankit Sachan1,
  2. Prashant Singh1,
  3. Seema Kaushal2 and
  4. Rajeev Kumar1
  1. 1Urology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  2. 2Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  1. Correspondence to Dr Ankit Sachan; ankicool007{at}


A man in his 50s presented with shortness of breath and was found to have a large paracaval mass, which on further evaluation with CT, showed a large heterogeneously enhancing mass lesion adjacent to right renal hilum. His 24-hour urinary metanephrines and nor-metanephrines were normal. In view of location and features on CT, paraganglioma was considered as a possibility. A 68Ga-DOTATATE positron emission tomography/CT demonstrated avidity in the lesion with maximum standardised uptake value of 16.5. He underwent right laparoscopic converted to open mass excision along with nephrectomy. Histopathological examination was suggestive of hyaline vascular Castleman disease.

  • Urological surgery
  • Adrenal disorders
  • Radiology

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  • AS and RK contributed equally.

  • Contributors RK is the guarantor and consultant urologist under whom the case was admitted. He performed the surgery and had the authority of final decision-making in every aspect of the case. He also helped write this paper and reviewed it before submission. AS is the urology resident who managed the case and involved with the patient from admission until discharge and also wrote the template of the article and took informed consent on the publication of this case report. PS is the fellow and involved in surgery and also responsible for helping write this case report. SK is the consultant pathologist involved in histopathological diagnosis of the case and proving histopathological images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.