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Postoperative radiotherapy for high-grade primary cardiac spindle cell sarcoma: a rare entity
  1. Tooba Ali1,
  2. Nasir Ali1,
  3. Laraib Khan1 and
  4. Khurram Minhas2
  1. 1Department of Oncology, Section Radiation Oncology, Aga Khan University, Karachi, Pakistan
  2. 2Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
  1. Correspondence to Dr Tooba Ali; tooba053{at}


A patient in her early 20s presented with blood-stained sputum and shortness of breath. Initially, she was treated for pneumonia. Later, upon exacerbation of symptoms, further investigations were done which exhibited a left atrial mass causing compression of contralateral atrium. She underwent surgical resection of the mass, which was initially mistaken as myxoma. However, histopathological correlation revealed spindle cell sarcoma with focal myogenic differentiation. This case report highlights the role of Radiation Therapy in adjuvant setting with promising impact on improving local control after R2 resection. Cardiac spindle cell sarcoma, being one of the rarest cardiac tumours reported to date, warrants establishment of a Rare Tumour Multidisciplinary Team for management of such malignancies.

  • Cardiothoracic surgery
  • Radiotherapy
  • Oncology
  • Cancer intervention
  • Chemotherapy

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content—TA, NA and LK. The following authors gave final approval of the manuscript—TA and NA.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.