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Acinetobacter radioresistens and Microbacterium paraoxydans endocarditis in patient with indwelling catheter and metastatic carcinoma
  1. Elizabeth Pinchman1,
  2. Benjamin Hoenig1,
  3. Gabriel Solorzano2 and
  4. Charles Martin2
  1. 1Medical Education, Albany Medical College, Albany, NY, USA
  2. 2Internal Medicine, Albany Medical Center, Albany, NY, USA
  1. Correspondence to Ms Elizabeth Pinchman; pinchme{at}amc.edu

Abstract

Acinetobacter radioresistens is a rare cause of nosocomial infection and is believed to confer antibiotic resistance to aggressive bacterial species. We present the first reported case of polymicrobial endocarditis caused by A. radioresistens and Microbacterium paraoxydans co-infection, a case of a woman in her late 60s with bacteraemia and ultimate finding of endometrial carcinoma. Bacteraemia with either agent in a previously healthy patient should prompt providers to search for underlying malignancy or immunological problem.

We support the use of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry for identifying these organisms in cultures, as well as the development of faster isolation techniques through PCR. Furthermore, we advocate for providers to order early antibiotic susceptibility testing, since our patient’s Microbacterium sp was not susceptible to meropenem unlike most Microbacterium reported in literature.

  • Valvar diseases
  • Infections
  • Malignant disease and immunosuppression
  • Gynecological cancer

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Footnotes

  • Contributors EP interviewed the subject, gathered data, wrote the case summary and edited the manuscript. BH was responsible for the literature review presented in the introduction and discussion sections. GS conducted the majority of editing and assisted in structuring the case report. CM also assisted in editing the manuscript, as well as providing direct patient care for this subject.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.