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Recurrent reactive infectious mucocutaneous eruption in a male adult patient associated with Mycoplasma pneumoniae, SARS-CoV-2 and rhinovirus
  1. Valerie van Dam1,
  2. Michiel Bonny2 and
  3. Soetkin Desmet1
  1. 1Dermatology, Algemeen Ziekenhuis Alma campus Eeklo, Eeklo, Belgium
  2. 2Dermatology, Algemeen Ziekenhuis Groeninge, Kortrijk, Belgium
  1. Correspondence to Dr Valerie van Dam; vandamvalerie{at}


We present a case of a man in his early 30s who developed four episodes of reactive infectious mucocutaneous eruption (RIME), in association with different infectious pathogens.

RIME is a recently implemented term to describe mucocutaneous eruptions associated with respiratory pathogens. These eruptions are characterised by predominant mucosal involvement of two or more mucous membranes and limited cutaneous involvement. The disease course and prognosis are mostly favourable, especially in recurrent episodes of RIME in the same patient. In recurrent episodes of RIME, Mycoplasma pneumoniae is often identified as the infectious trigger in the first episode.

  • Dermatology
  • COVID-19
  • Skin

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  • Contributors VvD and SD both treated the patient. VvD wrote the case report. SD and MB edited the case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.