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Life-threatening complication: the development of necrotising fasciitis in a preterm neonate with omphalitis
  1. Maira Jamal1,
  2. Kanza Ateeque2,
  3. Maida Binte Khalid Quddusi3 and
  4. Farah Naz Qamar3
  1. 1Pediatrics, Hamdard University College of Medicine and Dentistry, Karachi, Sindh, Pakistan
  2. 2Dow University of Health Sciences, Karachi, Sindh, Pakistan
  3. 3Paedriatrics, The Aga Khan University Hospital Main Campus, Karachi, Pakistan
  1. Correspondence to Dr Maida Binte Khalid Quddusi; maidaquddusi799{at}


Omphalitis is a mild medical condition that can turn severe in exceptional situations leading to necrotising fasciitis. The most common cause of omphalitis is umbilical vein catheterisation (UVC) where the cleanliness measures can be compromised. The treatment options for omphalitis include antibiotics, debridement and supportive care. Sadly, the fatality rate in such cases is high. This report is about a premature female baby who was admitted to a neonatal intensive care unit after her birth at 34 weeks of gestation. UVC was performed on her which led to abnormal changes in the skin around her umbilicus. Further tests revealed that she had omphalitis and was treated with antibiotics and supportive care. Unfortunately, her condition quickly worsened and she was diagnosed with necrotising fasciitis which ultimately resulted in her death. This report provides details about the patient’s symptoms, course of illness and treatment for necrotising fasciitis.

  • Neonatal intensive care
  • Neonatal and paediatric intensive care

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  • Contributors MJ : directly involved in patient care and management. She took the consent and wrote the largest share of report including case history and discussion. She also did all corrections and readied the final draft for submissions. KA: she prepared abstract, wrote introduction and did referencing. She is medical student and assisted. MJ in final draft preparation. MBKQ: she did initial critical review of case report, title edits, picture formatting and content alignment. She submitted the case report and will become the corresponding author. FNQ: she is the attending paediatrician, she did the final critical review and was also involved in management.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.