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Long-term follow-up of acute retinal necrosis with retinal detachment secondary to herpes simplex virus type 2 with a successful visual outcome
  1. Srinivasan Sanjay1,
  2. Shama Sharief2,
  3. Aishwarya Joshi1 and
  4. Naresh Kumar Yadav2
  1. 1Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, India
  2. 2Vitreo-retina, Narayana Nethralaya, Bengaluru, Karnataka, India
  1. Correspondence to Dr Srinivasan Sanjay; sanjaygroup24{at}


A man in his early 20s presented with acute loss of vision in his only eye, the left eye (OS), and was on oral steroids. He had lost vision in his right eye during his childhood and the cause was unknown. There was no history of trauma. Best-corrected visual acuity (BCVA) in OS was 20/100 and in the right eye was hand movements. OS showed non-granulomatous keratic precipitates on the cornea, anterior chamber flare 1+ and cell 1+, early cataract, vitreous haze and cells 2+ with nasal retinal detachment and superior full thickness retinitis. He underwent pars plana vitrectomy with intravitreal ganciclovir and barrage laser away from the necrotic retina. PCR for herpes simplex virus 2 was positive from the aqueous and vitreous sample. He was started on oral valacyclovir 1 g three times a day and continued on tapering dose of oral steroids. BCVA in OS at 6-month follow-up was 20/25.

  • Eye
  • Infections
  • Global Health
  • Infectious diseases
  • Retina

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  • Contributors SSanjay—design, data collection, analysis, manuscript writing, manuscript editing and intellectual content. SSharief—data collection, manuscript writing and editing. AJ—data collection, image editing and manuscript writing. NKY—design, data analysis, manuscript editing and intellectual content.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.