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Marked reactive thrombocytosis in a female with iron deficiency anaemia
  1. Vishnu Sharma1,
  2. Vansh Bagrodia2,
  3. Naman Modi2 and
  4. Tanishk Parchwani2
  1. 1Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India
  2. 2Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India
  1. Correspondence to Dr Vishnu Sharma; vanshbagrodia{at}


This case report presents the clinical evaluation and management of a female patient from a rural background who presented with leg pain, headache, weakness and irritability. Initial investigations revealed iron deficiency anaemia accompanied by a significantly elevated platelet count, prompting suspicion of an underlying myeloproliferative neoplastic disorder. However, subsequent genetic testing ruled out these mutations, suggesting a reactive response to iron deficiency anaemia rather than an independent neoplastic process. Treatment was focused on addressing the underlying iron deficiency anaemia, resulting in significant improvement in the patient’s blood profile and resolution of symptoms. Follow-up assessments demonstrated a complete normalisation of the blood profile and platelet counts, further supporting the efficacy of the treatment. This case highlights the importance of considering reactive thrombocytosis in the context of iron deficiency anaemia and emphasises the favourable response achieved through appropriate management strategies.

  • Haematology (incl blood transfusion)
  • Medical education

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation of results, drawing original diagrams and algorithms and critical revision for important intellectual content: VS, VB, NM and TP. The following author gave final approval of the manuscript: VS.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.