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Infectious Diseases
Non-typhoidal Salmonella enteritidis prosthetic valve endocarditis
  1. Bas W A van Kruijsbergen1,
  2. Janneke P Spiegelenberg2,
  3. Maarten van Lieshout1 and
  4. Maarten Heuvelmans3
  1. 1Department of Intensive Care Medicine, Ziekenhuis Rivierenland, Tiel, The Netherlands
  2. 2Department of Internal Medicine, Ziekenhuis Rivierenland, Tiel, The Netherlands
  3. 3Department of Medical Microbiology, Ziekenhuis Rivierenland, Tiel, The Netherlands
  1. Correspondence to Bas W A van Kruijsbergen; b.w.a.vankruijsbergen{at}students.uu.nl

Abstract

In this case, we present a rare cause of prosthetic valve endocarditis. A man in his 80s presented to the emergency department with fever and diarrhoea. The patient underwent a transcatheter aortic valve replacement 17 years earlier. A negative PCR result in faeces for Salmonella and positive blood cultures with Salmonella gave rise to the suspicion of an intravascular Salmonella infection, which was confirmed with a positron emission tomography. Due to the low prevalence of Salmonella endocarditis, there is no consensus on the most effective treatment. Guidelines recommend early surgery and long-term antimicrobial treatment in endocarditis with Gram-negative bacteria. In this case, surgery was not deemed feasible given the patient his advanced age and multiple comorbidities. Despite treatment with intravenous antibiotics, the patient succumbed to progression of endocarditis 37 days after admission.

  • Valvar diseases
  • Infections
  • Foodborne infections

https://doi.org/10.1136/bcr-2023-256540

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    Footnotes

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: BWAvK, MH, JS and MvL. The following authors gave final approval of the manuscript: BWAvK, MH, JS and MvL.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.