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First-reported case of vaginal late recurrence of Wilms tumor treated with complete pelvic exenteration
  1. Giada Pizzuti,
  2. Yolanda Quijano,
  3. Emilio Vicente and
  4. Riccardo Caruso
  1. General and Digestive Surgery Department, Hospital Universitario HM Sanchinarro, Madrid, Madrid, Spain
  1. Correspondence to Dr Riccardo Caruso; ricaruso2{at}


Late relapses of Wilms tumour are extremely uncommon but still represent possible events. Even more rarely Wilms tumours present as extrarenal neoplasms, for which it could be difficult to diagnose and treat them promptly.

We present a unique case of late recurrence of Wilms tumour 16 years after the primary diagnosis, with location in the gynaecological system. The relapse presented as a vaginal mass, and it gradually raised up to involve the majority of pelvic organs. We accurately studied the tumour extension, even realising a 3D preoperative reconstruction, and we managed to evaluate the patient with a multidisciplinary team involving general surgeons, urologists, gynaecologists and plastic surgeons. We finally decided for an extended surgical approach and realised a complete pelvic exenteration. Three months after surgery, the patient is in a good general condition, without major surgical complications and with no radiological signs of pelvic tumour relapse.

  • Cancer intervention
  • Cervical cancer
  • Oncology
  • Surgery
  • Surgical oncology

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: GP, RC. The following authors gave final approval of the manuscript: YQ, EV.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.