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Monochorionic twin pregnancy in a patient with type III osteogenesis imperfecta: a multidisciplinary challenge
  1. Kai Wei Lee1,2,
  2. May Un Sam Mok3,
  3. Hui Zhong Chai4 and
  4. Liying Yang2
  1. 1Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore
  2. 2Department of Obstetrics and Gynaecology, Singapore General Hospital, Singapore
  3. 3Department of Anaesthesiology, Singapore General Hospital, Singapore
  4. 4Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore
  1. Correspondence to Dr Kai Wei Lee; kaiwei.lee{at}


A woman with severe type III osteogenesis imperfecta spontaneously conceived a monochorionic, diamniotic twin pregnancy. Due to the severity of her condition, her pregnancy required close follow-up involving a multidisciplinary team, including high-risk obstetricians, anaesthetists, pulmonologists and respiratory therapists. Eventually, the twins were delivered via caesarean section at 26 weeks’ gestation.

We discuss the challenges and considerations in managing her high-risk pregnancy, highlighting the importance of multidisciplinary care in achieving a safe outcome for mother and babies.

  • Obstetrics and gynaecology
  • Pregnancy

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: KWL, LY. The following authors gave final approval of the manuscript: KWL, LY, MUSM, HZC.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.