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Lung transplant in chronic HIV infection
  1. Keerthi Yarlagadda1,
  2. Rachel Werne2 and
  3. Neeraj Sinha3
  1. 1Pulmonary and Critical Care Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
  2. 2Department of Internal Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
  3. 3Department of Pulmonary and Critical Care Medicine, Miami Transplant Institute, University of Miami, Jackson Health System, Miami, Florida, USA
  1. Correspondence to Dr Keerthi Yarlagadda; keerthi.yarlagadda{at}jhsmiami.org

Abstract

Lung transplantation is the treatment of choice for many end-stage chronic lung conditions. Chronic Human Immunodeficiency Virus (HIV) infection is considered a relative contraindication for lung transplantation. In the era of Highly Active Antiretroviral Therapy (HAART), there has been an increase in the number of HIV-positive patients living with chronic lung conditions. In this paper, we aim to summarise the available literature in the field of lung transplantation in HIV-positive patients. We also present our experience of an HIV-positive woman who underwent lung transplantation for chronic interstitial lung disease from an HIV-negative donor.

Careful candidate selection, along with management focused on closer monitoring, may result in favourable outcomes, including improved longevity among HIV-positive patients with chronic lung disease.

  • HIV / AIDS
  • Interstitial lung disease
  • Transplantation

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Footnotes

  • Contributors KY and NS participated in taking care of the patient when admitted and also as outpatient when discharged. RW contributed in drafting case presentation through a chart review. KY played a key role in literature review and drafting the main manuscript. NS supervised the trainees in drafting the manuscript and edited the manuscript as necessary.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.