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Maxillary osteomyelitis in a young female with osteopetrosis: unveiling an uncommon connection
  1. Jitendra Chawla1,
  2. Navaneeth Yerragudi1,
  3. Mithilesh Arumulla2 and
  4. Shrikanth Gunturur3
  1. 1Department of Dentistry, All India Institute Of Medical Sciences, Mangalagiri, Andhra Pradesh, India
  2. 2Department Of Radiodiagnosis, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India
  3. 3Department of Oral and Maxillofacial Surgery, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Krishna, Andhra Pradesh, India
  1. Correspondence to Dr Jitendra Chawla;{at}


Osteopetrosis encompasses a spectrum of conditions marked by heightened bone density due to faulty osteoclast-mediated bone resorption, leading to an accumulation of immature bone and thickened cortical structures. This condition gives rise to bone fragility, blood cell irregularities, nerve entrapment and growth challenges, all stemming from disrupted bone remodelling. Craniofacial distinctiveness, encompassing anomalies in the skull and jaw, is a frequent occurrence. Osteopetrosis presents a range of clinical signs, including facial and dental anomalies. The diagnostic process involves thorough clinical and radiological assessments, often obviating the need for genetic testing. Interestingly, few prior reports have delved into the specifics of craniofacial and dental issues in osteopetrosis. The presented case showcases rare occurrence of maxillary osteomyelitis. The diagnosis was established through a combination of history, clinical, radiographic and laboratory findings. The patient declined surgical intervention, leading to the implementation of conservative management involving regular irrigation alongside systemic antibiotic therapy.

  • Dentistry and oral medicine
  • Endocrinology
  • Mouth

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: SG, JC, NY and MA. The following authors gave final approval of the manuscript: JC.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.