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Intravitreal aflibercept for idiopathic choroidal neovascularisation in paediatric age
  1. Ana Rita Viana1,
  2. José Lemos1,
  3. Mariana Almeida Oliveira2 and
  4. Carla Teixeira1
  1. 1Ophthalmology, Hospital Pedro Hispano, Matosinhos, Portugal
  2. 2Ophthalmology, Hospital de Braga, Braga, Portugal
  1. Correspondence to Dr Ana Rita Viana; anaritamviana{at}


A boy in early adolescence presented with a 1-week history of visual acuity impairment in his right eye (RE). Fundus examination of the RE revealed an elevated yellow-greyish lesion in the inferior temporal juxtafoveolar area. Findings on optical coherence tomography, fluorescein angiography and optical coherence tomography angiography were compatible with active choroidal neovascularisation (CNV). In the absence of a primary ocular pathology and a potential systemic secondary cause, it was assumed an idiopathic aetiology of CNV. The child was treated with intravitreal injections of aflibercept, showing good anatomical and functional responses. No complications were recorded after the injections. CNV in children is a rare ocular condition that can lead to permanent visual acuity impairment. Although the therapeutic approach remains controversial, anti-vascular endothelial growth factor intravitreal injections represent a safe and effective therapeutic option for CNV in children.

  • Eye
  • Paediatrics (drugs and medicines)
  • Macula
  • Retina
  • Paediatric prescribing

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  • Contributors All authors participated in the first evaluation, diagnosis or follow up of the patient. ARV wrote the manuscript and gathered the clinical information and images. CT, JL and MAO decided the treatment and supported the writing of the manuscript. All authors discussed the results and commented on the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.