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Bilateral primary breast Burkitt’s lymphoma in pregnancy
  1. Ellery Altshuler1,
  2. Sarah Wheeler2 and
  3. Karen Daily2
  1. 1Department of Internal Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
  2. 2Department of Hematology and Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
  1. Correspondence to Dr Ellery Altshuler; ElleryAltshuler{at}


Pregnancy-associated cancer is defined as malignancy diagnosed during gestation or up to 1 year post partum. Treatment of cancer during pregnancy is complicated by the risk of harm to the fetus and limitations in safety data. Postpartum patients receiving chemotherapy, tyrosine-kinase inhibitors or hormonal agents should avoid breast feeding to avoid drug excretion in breast milk. Patients who will receive cytotoxic chemotherapy should be advised of the potential impact on their future fertility and offered fertility-preservation options. Breast cancer is the most common pregnancy-associated malignancy and is most frequently either invasive ductal or lobular carcinoma. Breast lymphoma is an exceedingly rare diagnosis that typically presents with unilateral disease in the seventh decade of life. Here, we present the case of a woman who presented with bilateral breast masses during the second trimester of pregnancy and was ultimately diagnosed with primary breast Burkitt’s lymphoma.

  • Breast cancer
  • Oncology
  • Chemotherapy
  • Carcinogenesis

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  • Contributors EA, SW and KD collectively conceived of the idea for the manuscript. EA wrote the original draft. SW and KD edited the initial draft. KD supervised the project. All authors read the final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.