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Splenic abscess caused by Cutibacterium acnes in a patient with multiple tooth extractions
  1. Madalyn Walsh1,
  2. Nicholas Wasko2,
  3. Andrew Joseph Simms3 and
  4. Jacob Hodges3
  1. 1Internal Medicine, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
  2. 2Internal Medicine—Neurology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
  3. 3Internal Medicine—Infectious Diseases, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
  1. Correspondence to Dr Madalyn Walsh; madalyn-walsh{at}uiowa.edu

Abstract

A woman in her 40s with a history of dental abscess presenting with a 3-month history of nightly fevers, malaise, fatigue and acutely worsening left flank pain was found to have a splenic abscess replacing almost the entire splenic parenchyma on abdominal CT. Abscess aspirate showed Gram-positive rods, and both aerobic and anaerobic cultures grew Cutibacterium acnes (previously Propionibacterium acnes), a common member of the skin microbiome. Prior case reports of C. acnes splenic abscess all involved parental inoculation via needle use. However, in the context of no percutaneous needle exposure and multiple tooth extractions immediately preceding her symptoms, the most likely source of her infection is oral flora with haematogenous or lymphatic spread to the spleen.

  • Dentistry and oral medicine
  • Infections
  • Infectious diseases
  • Surgery

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Footnotes

  • Contributors MW was the general medicine resident caring for patient, drafted and revised portions of the manuscript, submitted the manuscript for publishing. NW was the infectious disease resident caring for patient, drafted and revised portions of the manuscript. AJS was the infectious disease fellow caring for patient, obtained and formatted figures, revised manuscript. JH was the staff physician caring for patient, revised manuscript, gave insight into publishing and journal selection.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.