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Hypertriglyceridemia with pancreatitis at disease onset in systemic lupus erythematosus
  1. Mahendra Atlani1,
  2. Girish C Bhatt2,
  3. Divya Tarachandani3 and
  4. Venkatesh Charan4
  1. 1Nephrology, AIIMS Bhopal, Bhopal, Madhya Pradesh, India
  2. 2Division of Pediatric Nephrology, Department of Pediatrics, AIIMS Bhopal, Bhopal, Madhya Pradesh, India
  3. 3General Medicine, All India Institute of Medical Science—Bhopal, Bhopal, Madhya Pradesh, India
  4. 4Medicine, AIIMS Bhopal, Bhopal, Madhya Pradesh, India
  1. Correspondence to Dr Mahendra Atlani; mahendra.nephro{at}


Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the presence of several autoantibodies, immune complex formation and multiple organ system involvement. SLE has a wide range of manifestations involving nearly all organ systems. Hypertriglyceridemia (HTG) in SLE is a well-established and a common abnormality, which is generally mild and not included in the diagnostic criteria of SLE. HTG as the initial manifestation of SLE in adult patients in association with acute pancreatitis at levels below 1000 mg/dL has not been previously reported. Here, we report a case of rare presentation of moderate HTG (TG-869 mg/dL) with pancreatitis at disease onset in an adult women which later proved to be due to SLE and progressed to levels of severe HTG during the course of illness. The patient was successfully treated with plasma exchanges and cyclophosphamide.

  • pancreatitis
  • systemic lupus erythematosus
  • connective tissue disease

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  • Twitter @dialysis, @Dr divya Tarachandani

  • Contributors MA provided and cared for the patient. DT and VC collected data. MA and GCB and DT all contributed in preparation, editing and review of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.