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Paraneoplastic leukemoid syndrome in squamous cell carcinoma of the forearm
  1. Snehasis Das,
  2. Oseen Hajilal Shaikh,
  3. Sagar Prakash and
  4. Balasubramanian Gopal
  1. Surgery, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, India
  1. Correspondence to Dr Balasubramanian Gopal; drbala18{at}


The paraneoplastic leukemoid reaction is a rare haematological paraneoplastic syndrome, which is typically seen with solid tumours and squamous cell carcinomas. As an indication of bone marrow infiltration and malignancy involvement, it indicates a poor outcome and a grave prognosis. We report a woman in her 50s, who presented with an ulcer over the right forearm. Biopsy revealed squamous cell carcinoma. The patient underwent radiological investigations, which showed the presence of metastatic squamous cell carcinoma. Incidentally, the patient was found to have leucocytosis, which was attributed to a paraneoplastic leukemoid reaction, after ruling out all other causes of leukemoid reaction. Due to metastatic disease, the patient was planned for palliative radiotherapy and the best supportive care.

  • Surgical oncology
  • General surgery
  • Surgery

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  • Contributors Preparation of the manuscript—SD. Collection of the data—SP. Interpretation of the data—OHS. Critical revision—BG.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.