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Testicular yolk sac tumour metastasis to the L2 vertebra
  1. Gisela Murray1,
  2. Orlando De Jesus1,
  3. Maria Correa-Rivas2 and
  4. Jorge I Cheverez-Ocasio2
  1. 1Department of Neurosurgery, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
  2. 2Department of Pathology and Laboratory Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
  1. Correspondence to Dr Orlando De Jesus; drodejesus{at}


The role of surgery for metastases to the vertebra from yolk sac tumours has not been established. The main treatment for disseminated disease is chemotherapy. We present a man in his 30s with a left orchiectomy for a testicular mixed germ cell tumour with a prominent yolk sac component who, 12 months later, developed an asymptomatic metastasis to the L2 vertebra unresponsive to chemotherapy and radiotherapy. The patient underwent resection of the L2 vertebral body, leaving a small residual tumour anterior to the vertebra attached to the great vessels. Pathology confirmed the diagnosis of a metastatic testicular yolk sac tumour in the vertebra. The postoperative MRI 6 months later demonstrated significant expansion of the tumour at the soft tissues anterior to the expandable titanium cage encasing the great vessels and extending to the paraspinal areas. Additional salvage surgery was not recommended because of the advanced stage of the tumour.

  • Neuroimaging
  • Neurooncology
  • Urological cancer
  • Pathology
  • Neurosurgery

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  • Contributors Conception and design: GM and ODJ. Drafting the manuscript: GM, ODJ, MC-R and JCO. Approval of manuscript: GM, ODJ, MC-R and JCO.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.