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Metachronous parathyroid adenoma characterised by recurrent nephrolithiasis
  1. Kiera Brigh Turner1,
  2. Jonathan Wideroff2 and
  3. Lawrence Brickman1
  1. 1Charles E Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA
  2. 2General Surgery, Delray Medical Center, Delray Beach, Florida, USA
  1. Correspondence to Kiera Brigh Turner; kieraturner2019{at}


Hyperparathyroidism is often diagnosed after identifying hypercalcaemia through routine testing in asymptomatic patients; however, many patients experience severe and painful symptoms related to their diagnosis, including nephrolithiasis and bone pain with osteoporosis. Double adenomata are an uncommon cause of hyperparathyroidism, and they occasionally occur metachronously with recurrent symptoms years apart. This case report examines a woman in her 60s with a history of parathyroid adenoma 9 years earlier who presented with recurrent nephrolithiasis. She was found to have a recurrence of primary hyperparathyroidism after more than a year of recurrent urinary tract infections, nephrolithiasis and bacteraemia. A neck exploration revealed a metachronous parathyroid adenoma, which was removed with complete resolution of symptoms. Her case demonstrates the importance of evaluating patients with nephrolithiasis for hyperparathyroidism and communicating abnormal laboratory results with the patient in a hospital setting. It also provides the opportunity to examine the rare diagnosis of a metachronous parathyroid adenoma.

  • Endocrinology
  • Calcium and bone
  • Head and neck surgery

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  • Contributors KBT drove the conception of the work, gathered the clinical details, drafted the report, created the figures and revised the manuscript. JW provided critical review and advice, and edited the final manuscript. LB provided critical review and reviewed the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.