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Ventricular sense response pacing in cardiac resynchronisation therapy: a potentially effective treatment option for heart failure in patients with atrial fibrillation
  1. Motoaki Higuchi,
  2. Tomoaki Hasegawa and
  3. Yoshiro Chiba
  1. Cardiology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
  1. Correspondence to Dr Motoaki Higuchi; motoakihiguchi{at}


Cardiac resynchronisation therapy (CRT) for atrial fibrillation (AF) with intraventricular conduction and low cardiac output may not allow high-frequency biventricular pacing (BiVP). To this end, drugs and ablation treatments are commonly used. Ventricular sense response pacing (VSRP) senses self-pulse and can produce a state comparable with BiVP. If found to be effective for cardiac resynchronisation, the benefit of CRT with VSRP is expected to extend to patients with AF. Herein, we describe the case of a man in his early 60s with low cardiac output caused by AF and left bundle branch block. CRT-defibrillator (CRT-D) implantation was performed, and VSRP was applied. We found VSRP to be more effective in improving cardiac function than drug-induced BiVP. VSRP may become an effective treatment option following CRT-D implantation in patients with AF.

  • cardiovascular medicine
  • Heart failure
  • interventional cardiology

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  • Contributors MH was involved in the patient’s clinical management and drafting of the manuscript. TH edited the draft. YC agreed to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.