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Unusual complication of Herpes simplex encephalitis: complete Klüver-Bucy syndrome
  1. Melissa Hernandez-Vega1,
  2. Sandra Badial-Ochoa1,
  3. Francisco Javier Rivas-Ruvalcaba1 and
  4. Ildefonso Rodriguez-Leyva1,2
  1. 1Neurology Service, Internal Medicine Department, Hospital Central Dr Ignacio Morones Prieto, San Luis Potosi, Mexico
  2. 2Universidad Autonoma de San Luis Potosi - Facultad de Medicina, San Luis Potosi, Mexico
  1. Correspondence to Dr Ildefonso Rodriguez-Leyva; ilrole{at}


Klüver-Bucy syndrome is a rare neurobehavioral disorder caused by a bilateral temporal lobe lesion affecting the hippocampus and amygdala; clinically characterised by hyperorality, hypermetamorphosis, placidity, altered sexual behaviour, eating, disorders and visual impairment, agnosia and amnesia. However, the complete syndrome is rarely seen, and diagnosis does not require all the symptoms to be manifested simultaneously.

We describe a patient who developed a complete Klüver-Bucy syndrome secondary to bilateral temporal involvement due to herpetic encephalitis.

  • Memory Disorders
  • Epilepsy and seizures
  • Headache (including migraines)
  • Infection (neurology)
  • Neuroimaging

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  • Contributors IR-L, MH-V, SB-O and FJR-R participated in the planning, writing and editing of the report. IR-L is the corresponding author. IR-L participated in asking the family to sign the consent form.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.