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Management of acute colonic pseudo-obstruction in a neutropenic patient
  1. Suzanne Xu,
  2. Shreyak Sharma and
  3. Farid Jadbabaie
  1. Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA
  1. Correspondence to Suzanne Xu; suzanne.xu132{at}


Acute colonic pseudo-obstruction, also known as Ogilvie’s syndrome, is a rare condition involving acute large bowel dilatation without mechanical obstruction. Management begins with conservative treatment and may include pharmacological therapy, colonoscopic decompression and surgery. Timely resolution is important due to the increased risk of bowel perforation and ischaemia associated with colonic dilatation. However, conditions such as neutropenia that place patients at an elevated risk of infection may limit treatment options. We report a case of acute colonic pseudo-obstruction in a neutropenic elderly man resistant to conservative measures and neostigmine and discuss the additional management considerations in an immunocompromised patient.

  • Endoscopy
  • Medical management

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  • Contributors All authors made substantial contributions to the conception of the case report. SLX and SS drafted the work, and FJ provided critical revisions. All authors approved the final version to be published and agree to be accountable for the content of the work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.