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Case Reports: Rare disease
Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature
  1. Bikash Ranjan Mahapatra1,
  2. Anupam Muraleedharan1,
  3. Saroj Kumar Das Majumdar1 and
  4. Amit Kumar Adhya2
  1. 1Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
  2. 2Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
  1. Correspondence to Dr Saroj Kumar Das Majumdar; sarojmajumdar{at}gmail.com

Abstract

Primary gastric melanoma is a rare clinical finding. It presents with upper gastrointestinal symptoms like abdominal pain, weight loss and melaena. It is often difficult to differentiate a primary gastric melanoma from primary cutaneous melanoma with gastric metastasis. Upper gastrointestinal endoscopy and biopsy of the lesion for histopathology and immunohistochemistry help to reach a definite diagnosis. We report a case of primary gastric melanoma with metastases to the liver and bone. The patient was treated with palliative radiotherapy, palliative chemotherapy and a bone-stabilising agent.

  • Cancer intervention
  • Malignant disease and immunosuppression
  • Gastric cancer
  • Radiotherapy
  • Pathology

https://doi.org/10.1136/bcr-2022-249312

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    Footnotes

    • Contributors SKDM was the head of the treatment team, identified the case, and has seen and approved the final manuscript. BRM was involved in the collection of data and follow-up of the patient, supervised the investigations, and has seen and approved the final manuscript. AM was involved in the collection of data and preparing the abstract, and has seen and approved the final manuscript. AKA was the head of the pathology team and has seen and approved the final manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.