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Laryngeal histoplasmosis: masquerading malignancy
  1. Devendra Kumar Gupta1,
  2. Deepika Tanwar1,
  3. Bhaumik Patel1 and
  4. Vikram Singh2
  1. 1ENT-HNS, Army Hospital Research and Referral, New Delhi, Delhi, India
  2. 2Pathology, Army Hospital Research and Referral, New Delhi, Delhi, India
  1. Correspondence to Dr Deepika Tanwar; deepika03ddt{at}


Laryngeal histoplasmosis is a very rare cause of laryngitis which is encountered usually in the immunosuppressed states but can also occur in immunologically intact status. We report a rare case of laryngeal histoplasmosis in a man in his 60s, a chronic smoker who presented with a history of progressive hoarseness for 3 months. The glottic growth was biopsied. The rarity of diagnosis was aided by histopathological examination of the tissue, which revealed histoplasmosis. Management was done with intravenous liposomal amphotericin B and oral itraconazole with complete resolution of symptoms.

  • Infections
  • Head and neck cancer
  • Ear, nose and throat
  • Ear, nose and throat/otolaryngology

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  • Contributors DKG: planning of treatment, conducting the surgery, idea of publication in BMJ and proofreading. DT: writing of the manuscript, obtaining consent from the patient. BP: collection of data including picture and review of literature. VS: principal pathologist.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.