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Use of a synthetic biodegradable temporising matrix after necrotising fasciitis infection of the thigh
  1. Daniah ALNafisee1,
  2. Maire-Caitlin Casey1 and
  3. Jack L Kelly2
  1. 1Plastic and Reconstructive Surgery, University Hospital Galway, Galway, Ireland
  2. 2Department of Plastic and Reconstructive Surgery, Galway University Hospitals, Galway, Ireland
  1. Correspondence to Dr Daniah ALNafisee; dnafisee{at}


Biodegradable temporising matrix (BTM NovoSorb; PolyNovo, Melbourne, Australia) is a novel synthetic polyurethane dermal substitute. Licensed in Europe in 2020, it was developed primarily for reconstruction of infected wounds. We present a case of a healthy man in his 60s with necrotising fasciitis of his left thigh. His medical history was significant for recurrent left thigh liposarcoma that was treated years earlier with surgical excision and adjuvant radiotherapy. The affected area was within the previously irradiated tissue, debrided down to fascia and dressed with a vacuum-assisted closure to help regenerate the wound bed. Reconstruction options were limited by having a circumferential thigh defect that was infected. Following the use of NovoSorb BTM, the area was dressed with Acticoat Flex 7 antimicrobial barrier dressing for 5 weeks. Patient mobilisation was permitted. The material integrated very well and formed a soft, pliable healthy dermal layer that was autografted with split thickness skin grafts. This resulted in durable cover of the thigh with good aesthetic contour and minimal contracture.

  • Infections
  • Skin
  • Plastic and reconstructive surgery

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  • Contributors DA took pictures, assisted in surgery and wrote the manuscript. JK and MCC performed the surgery, initiated and supervised the project. All authors revised the manuscript and followed up the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.