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Case Reports: Unusual association of diseases/symptoms
An unusual ocular manifestation of multiple myeloma
  1. Robert McGrath1,
  2. Shane Whitlow1,
  3. Grace Anne McCabe2 and
  4. Elizabeth Margaret McElnea1
  1. 1Ophthalmology Department, University Hospital Galway, Galway, Ireland
  2. 2Ophthalmology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
  1. Correspondence to Dr Shane Whitlow; shanewhitlow{at}hotmail.com

Abstract

A man in his 70s with a history of multiple myeloma presented with a 4-day history of right ptosis and a rapidly enlarging upper eyelid mass. On examination, a large, firm, smooth, pink lesion was found to descend from the conjunctiva of the superior fornix. The patient underwent excision biopsy. Histopathological analysis demonstrated monoclonal plasma cells expressing light-chain kappa, consistent with extramedullary plasmacytoma. Clinical ophthalmic manifestations of multiple myeloma are rare but also diverse. Ocular surface manifestations of multiple myeloma are extremely uncommon. Variable examination findings mean those involving the conjunctiva and may be particularly challenging to diagnose. Secondary ocular extramedullary plasmacytoma, despite its rarity, should be considered in patients with multiple myeloma.

  • ophthalmology
  • haematology (incl blood transfusion)
  • oncology

http://dx.doi.org/10.1136/bcr-2021-247863

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    Footnotes

    • Correction notice This article has been corrected since it was first published online. The article title has been updated.

    • Contributors RMc and GMc: writing and editing; SW: writing (original draft) and editing; EMc: conceptualisation, review, editing and supervision.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.