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  • Gastrocutaneous fistula and gastrointestinal bleeding due to left superior epigastric artery haemorrhage as a rare complication of anterior gastropexy

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Gastrocutaneous fistula and gastrointestinal bleeding due to left superior epigastric artery haemorrhage as a rare complication of anterior gastropexy
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  • Published on: 19 August 2024
    Nicorandil as a plausible cause of gastrocutaneous fistula
    • Anette Bygum, Dermatologist University of Southern Denmark, Odense, Denmark
    • Other Contributors:
      • Jakob Drivenes, Resident

    Andrea-Ferreira et al. reported an interesting case of an elderly lady with gastrocutaneous fistula and gastrointestinal bleeding after anterior gastropexi. A mucosal biopsy from gastric tissue showed nonspecific inflammation.
    This patient later consulted dermatology due to several skin and mucosal ulcers. Her long medication list included nicorandil, which is known to induce ulcers and fistulas. After stopping this drug, all her skin and mucosal lesions resolved within 1 month.
    We suggest, that her gastrointestinal complications were also related to nicorandil, which she had taken for 3 years before undergoing her first surgery. The time course and histopathological findings are well in accordance with nicorandil induced skin and mucosal lesions.
    We have just published the case with focus on nicorandil.

    Drivenes JL, Bygum A. Spontaneous Mucocutaneous Ulcerations: A Quiz. Acta Derm Venereol 2024 Aug 5.

    Conflict of Interest:
    None declared.