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Complexities in diagnosing and treating endophthalmitis in the post stem cell transplant setting
  1. Peter Conlon1,
  2. Margaret Creedon2,
  3. Elaine Houlihan2 and
  4. Sadhbh O'Rourke2
  1. 1Haematology Department, St James' Hospital, Dublin, Ireland
  2. 2Clinical Microbiology, HSE, Dublin, Ireland
  1. Correspondence to Dr Peter Conlon; peter.conlon92{at}


Endophthalmitis is a rare but sight-threatening manifestation of systemic infection. Immunosuppression is a well-recognised risk factor for development of endophthalmitis. Determining the aetiology can be complex, particularly in the context of immunosuppression, we present the diagnostic and treatment dilemmas associated with a patient who complains of blurred vision 2 weeks following an allogeneic stem cell transplant for refractory Hodgkin’s disease. We demonstrate that in the context of immunosuppression post stem cell transplantation, a broad differential should be maintained until a microbiological diagnosis can be confirmed. In particular, we evaluate how clinical suspicion can diverge from typical fundoscopic findings in the diagnosis of endophthalmitis.

  • Haematology (incl blood transfusion)
  • Infectious diseases
  • Ophthalmology

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  • Contributors All authors were involved in the conception of this report and contributed substantially to the writing and submission of this report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.