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Case Reports: Findings that shed new light on the possible pathogenesis of a disease
Acute portal venous thrombosis as an extrahepatic manifestation of acute hepatitis A infection
  1. Ahmad Abulawi1,
  2. Ali AL-Tarbsheh1,
  3. Omar Tageldin2 and
  4. Asra Batool2
  1. 1Department of Medicine, Albany Medical College, Albany, New York, USA
  2. 2Department of Gastroenterology, Albany Medical College, Albany, New York, USA
  1. Correspondence to Dr Ahmad Abulawi; abulawa{at}amc.edu

Abstract

Among the many potential causes and risk factors for acute portal venous thrombosis, viral hepatitis has been regarded as a rare associated condition. We present the first case in the literature of a 30-year-old previously healthy male who presented with acute portal venous thrombosis associated with acute hepatitis A virus (HAV) infection, describing the probable pathophysiology mechanism, work-up and treatment pursued. We encourage that hepatitis A serological markers should be routinely included in the investigation for acute portal venous thrombosis of unknown aetiology, in unvaccinated patients with risk factors of a recent HAV exposure.

  • Venous thromboembolism
  • Gastrointestinal system
  • Infection (gastroenterology)
  • Hepatitis other
  • Haematology (incl blood transfusion)

https://doi.org/10.1136/bcr-2022-250177

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    Footnotes

    • Correction notice This article has been corrected since it was first published online Asra Batool was incorrectly listed as Batool Asra.

    • Contributors AA: writing—original draft, reviewed the literature, revised the manuscript for intellectual content and approved the final manuscript. AA-T: writing—reviewing and editing, reviewed the literature, revised the manuscript for intellectual content and approved the final manuscript. OT and BA: writing—reviewing and editing, revised the manuscript for intellectual content and approved the final manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.