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Ruptured retinoblastoma: management in a rare case scenario
  1. Aayesha Khanum,
  2. Thirumalesh Mochi Basavaraj and
  3. Gagan Dudeja
  1. Narayana Nethralaya, Bangalore, India
  1. Correspondence to Dr Thirumalesh Mochi Basavaraj; thirumaleshmb{at}


A preschool child presented with white reflex in left eye since 2 months. Examination under anaesthesia revealed left eye retinoblastoma group D as per international classification of retinoblastoma. In collaboration with medical oncologist, systemic chemotherapy was started. After two cycles of systemic chemotherapy, tumour ruptured into the vitreous cavity suspending the tumour cells in the vitreous jelly. After a combination of systemic and intravitreal chemotherapy with adjuvant transpupillary thermotherapy of the residual retinal tumour, retinoblastoma regressed completely with corresponding flat scar.

  • Oncology
  • Ophthalmology
  • Retina

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  • Contributors AK: writing original draft, reviewing and editing. TMB: conceptualisation and supervision. GD: project administrator.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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