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Intrahepatic renal cell carcinoma implantation along a percutaneous biopsy and cryoablation probe tract
  1. David Maxwell Galambos1,
  2. Aliaksei Salei1,
  3. Soroush Rais-Bahrami2 and
  4. Rakesh K Varma1
  1. 1Division of Interventional Radiology, Department of Radiology, The University of Alabama Heersink School of Medicine, Birmingham, Alabama, USA
  2. 2Department of Urology, The University of Alabama Heersink School of Medicine, Birmingham, Alabama, USA
  1. Correspondence to Dr David Maxwell Galambos; dgalambos{at}


A man in his 60s underwent percutaneous biopsy and cryoablation of a right upper pole clear cell renal cell carcinoma followed by repeat cryoablation 8 months later for possible residual disease. The patient was followed with imaging with documented stability for 19 months after repeat ablation. However, imaging at 32 months demonstrated intrahepatic nodular enhancing lesions along the initial percutaneous biopsy and ablation tract, consistent with metastatic implantation. The patient underwent repeat percutaneous biopsy and two rounds of microwave ablation for treatment of the intrahepatic implants, with no residual disease at 10 months postablation. While needle tract seeding is a known complication of percutaneous manipulation of various abdominopelvic malignancies, there have been no prior reports of intrahepatic metastatic implants related to percutaneous renal cell carcinoma ablation. Awareness of this potential complication is important for treatment planning, informed consent and surveillance. This report shares our experience of the management of intrahepatic metastatic implants.

  • Cancer intervention
  • Hepatic cancer
  • Urological cancer
  • Interventional radiology
  • Renal intervention

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  • Contributors DMG wrote the first draft and first revision of the case report. AS edited the case report and first revision. SR-B and RKV reviewed and approved the final version of the case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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