Article Text

Download PDFPDF
Two secondary localisation of non-Hodgkin’s lymphomas in the upper gastrointestinal tract
  1. Natale Calomino1,
  2. Daniele Fusario1,
  3. Emanuele Cencini2 and
  4. Stefano Lazzi3
  1. 1Department of Medicine, Surgery and Neuroscience, University of SIena, Siena, Italy
  2. 2Unit of Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy
  3. 3Department of Medical Biotechnologies, University of Siena, Siena, Italy
  1. Correspondence to Dr Natale Calomino; natale.calomino{at}


Extranodal non-Hodgkin’s lymphomas of the gastrointestinal tract represent 30%–40% of all extranodal lymphomas. Gastric lymphomas are increasingly described in the literature due to the development of diagnostic techniques and the increased incidence, together with the reduced incidence of gastric solid neoplasms. Significant diagnostic difficulties are determined by the non-specificity of the symptoms, which are mostly chronic, characterised by a slow progression. Localisation in the small intestine often appears as surgical urgency, due to the development of an intestinal obstruction or enterorrhagia. We present two cases of extranodal diffuse large B-cell lymphoma localisation, presented as a secondary lesion localised in the first one in the stomach, and in the second one in the first duodenal portion.

  • Gastrointestinal surgery
  • General surgery
  • Small intestine cancer
  • Haematology (incl blood transfusion)

Statistics from


  • Contributors NC conceived the study, participated in clinical data and drafted the manuscript. DF conceived the study, drafted and reviewed the manuscript. EC and SL provided language help and contributed to the manuscript draft. All authors read and approved the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.