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Sphenoid sinus cholesterol granulomas presenting with abducens nerve palsy
  1. Manon Doucet1,
  2. Daniel Farishta2,
  3. Jehan Abdulsattar3 and
  4. Michael Yim2
  1. 1Otolaryngology, University of Louisville, Louisville, Kentucky, USA
  2. 2Otolaryngology, LSU Health Shreveport, Shreveport, Louisiana, USA
  3. 3Pathology, LSU Health Shreveport, Shreveport, Louisiana, USA
  1. Correspondence to Dr Michael Yim; michael.yim{at}


We discuss two patients who presented with sphenoid sinus cholesterol granulomas and associated unilateral abducens nerve palsies. Two case reports from our institution are reported. A literature review of available articles is presented, discussing both cholesterol granulomas of the sphenoid sinus and sphenoid sinus lesions that present with unilateral abducens palsy. A total of nine cases of sphenoid sinus cholesterol granulomas have been previously reported in the literature. A wide variety of sphenoid sinus pathologies can present with unilateral abducens nerve palsies, however no sphenoid sinus cholesterol granulomas with this presentation were found in the literature. In conclusion, cholesterol granulomas should be included in the differential when a patient presents with an expansile mass of the sphenoid sinus and associated unilateral abducens nerve palsy.

  • Ear, nose and throat/otolaryngology
  • Ear, nose and throat

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  • Contributors DF, MY and MD contributed to the writing, editing and organisation of the manuscript. JA contributed the pathological images and did pathological examination of those images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.