Article Text

Download PDFPDF
Balloon pulmonary angioplasty in inoperable chronic thromboembolic pulmonary hypertension
  1. Ana Rita Pereira1,
  2. Rita Calé1,
  3. Filipa Ferreira1 and
  4. Helder Pereira1,2,3
  1. 1Cardiology Department, Hospital Garcia de Orta EPE, Almada, Setúbal, Portugal
  2. 2Cardiovascular Center of the University of Lisbon, Lisboa, Portugal
  3. 3Lisbon School of Medicine of the University, Lisboa, Portugal
  1. Correspondence to Professor Helder Pereira; hhpereira{at}


Balloon pulmonary angioplasty (BPA) is an emerging treatment for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or residual/recurrent pulmonary hypertension after pulmonary thromboendarterectomy. We report two patients with inoperable and severe CTEPH who were submitted to the BPA programme after optimised treatment with long-term oxygen therapy (LTOT) and pulmonary vasodilator drugs, including prostacyclin analogues. They experienced a significant improvement in exercise capacity, oxygenation, right ventricular function and pulmonary haemodynamics. This improvement allowed withdrawal from LTOT and prostacyclin analogues therapies and, consequently, improved patients’ quality of life and reduced future health-related costs. The reported clinical cases intend to highlight the effectiveness of BPA in patients with inoperable CTEPH for whom the only available therapy was, until recently, the pulmonary vasodilator drugs.

  • pulmonary embolism
  • pulmonary hypertension
  • interventional cardiology
  • interventional radiology

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors ARP was responsible for drafting the manuscript; RC was the main operator of the percutaneous procedures and revised the manuscript; FF belongs to the pulmonary hypertension group and was responsible for revising the manuscript; HP is the head of department and finally approved the manuscript submitted.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.