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Rare early presentation of bilateral compressive optic neuropathy with complete vision loss from nasopharyngeal carcinoma
  1. Yongyao Kong and
  2. Gee Jin Ng
  1. Department of Neurology, National Neuroscience Institute, Singapore
  1. Correspondence to Dr Yongyao Kong; yongyaokong{at}


Nasopharyngeal carcinoma is very rarely associated with bilateral vision loss, and only in advanced disease. We report a case of bilateral severe compressive optic neuropathy as a first presentation from massive nasopharyngeal carcinoma with poor visual outcome despite corticosteroid, chemotherapy and radiotherapy. Red flag symptoms and signs of mass lesions in the posterior nasal space should be investigated and treated promptly to prevent devastating visual and prognostic consequences.

  • neurology
  • cranial nerves
  • visual pathway
  • ear
  • nose and throat/otolaryngology
  • radiology

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  • Contributors YK provided care for the patient, performed the literature review and wrote the manuscript. GJN contributed to the literature review and the writing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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