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Duodenal gastrointestinal stromal tumour imitating as pancreatic head tumour
  1. Vaibhav Kumar Varshney1,
  2. Raghav Nayar1,
  3. Taruna Yadav2 and
  4. Sudeep Khera3
  1. 1Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
  2. 2Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
  3. 3Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
  1. Correspondence to Dr Vaibhav Kumar Varshney; drvarshney09{at}


Duodenal gastrointestinal stromal tumours (D-GISTs) are a rare disease. It may arise commonly from the second or third part of the duodenum and can be erroneously diagnosed as a pancreatic head tumour due to proximity and morphology on imaging studies. We present a case of a 60-year-old woman who presented with abdominal pain and was diagnosed as a case of pancreatic neuroendocrine tumour on radiologic imaging and granulomatous lesion on aspiration cytology. A ~5×3 cm mass was noted in the pancreatic head on laparotomy, and pancreatoduodenectomy was performed. Histopathology reported an exophytic GIST arising from the second part of the duodenum. Hence, D-GIST can invade the pancreas and mimic pancreatic head tumours; therefore, these tumours should be kept in the differential diagnosis of an atypical pancreatic head mass.

  • stomach and duodenum
  • pancreatic cancer
  • pathology
  • gastrointestinal surgery
  • radiology

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  • Contributors VKV and RN were involved as the treating surgeons and management of the patient. SK and TY were involved in the diagnosis of the disease. VKV, RN and TY were involved in writing the initial draft of the manuscript. All authors contributed to refining the study and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.