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GIST presenting as refractory iron-deficiency anaemia in paediatric patient
  1. Eman Al Atrash1,
  2. Mohammad Fahed Abdullah2,
  3. Joseph Pressey3 and
  4. Shyam Mohan4
  1. 1Department of Pediatrics, Division of Gastroenterology, Sheikh Khalifa Medical City, Abu Dhabi, UAE
  2. 2Department of Pediatrics, Division of Oncology and Hematology, Sheikh Khalifa Medical City, Abu Dhabi, UAE
  3. 3Department of Pediatrics, Division of Hematology and Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA
  4. 4Department of Radiology, Sheikh Khalifa Medical City, Abu Dhabi, UAE
  1. Correspondence to Dr Eman Al Atrash; emanalatrash8{at}


Gastrointestinal stromal tumours (GISTs) are very rare gastrointestinal (GI) mesenchymal tumours affecting only 0.02 children/million/year below the age of 14 years. We reported a 9-year-old girl presented to emergency department with pallor and haemoglobin of 50 g/L. Extensive workup for anaemia suggested iron-deficiency anaemia secondary to GI loss. Ultimately after blood transfusion of packed cells, she was discharged with a haemoglobin of 92 g/L with iron supplementation. Upper endoscopy showed incidental antral nodularity with biopsy proven helicobacter gastritis and an isolate 3–4 cm suspicious mass in the lesser curvature. Abdomen imaging confirmed the gastric mass in addition to two lesions, one retroperitoneal and one paraspinal. She undergone open laparotomy with complete surgical resection of the gastric and retroperitoneal masses with histological confirmation of GIST and paraganglioma. This case emphasises the importance of proper examination of the stomach at endoscopy and to illustrate that although anaemia is common in paediatric age group it may be reflect serious medical condition even in normal looking child.

  • paediatrics
  • GI bleeding
  • helicobacter pylori
  • gastric cancer
  • pathology

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  • Contributors EAA collected and reviewed the literature on the subject and wrote the paper. SM provided the images and the captions. JP and MFA provided the final revision and approval of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.