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Use of platelet-rich plasma in irradiated patients to treat and prevent complications of head and neck surgery
  1. Chiara Bramati1,2,
  2. Matteo Biafora1,
  3. Andrea Galli1 and
  4. Leone Giordano1
  1. 1Otorhinolaryngology - Head & Neck Surgery Department, IRCCS Ospedale San Raffaele, Milano, Lombardia, Italy
  2. 2School of Medicine, Vita-Salute San Raffaele University, Milano, Lombardia, Italy
  1. Correspondence to Dr Leone Giordano; giordano.leone{at}


Nowadays, many patients facing head and neck oncological surgery have a history of tissue irradiation. This represents an important risk factor for postsurgical complications, including dehiscences and fistulas. Platelet-rich plasma (PRP) obtained from the patient’s blood represents an easy, fast and inexpensive method for the prevention and treatment of such complications. We present three cases of previously irradiated patients in which PRP was successfully used to prevent and treat postsurgical complications.

  • Ear, nose and throat/otolaryngology
  • Head and neck cancer
  • Head and neck surgery

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  • Contributors GL had the idea for the article; CB wrote the article; AG and MB proofread the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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