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Rare case of littoral cell angioma recognised on CT simulation for adjuvant radiation treatment for early stage breast cancer
  1. Alexander Yaney1,
  2. Daniel Jones2,
  3. Kyle A Perry3 and
  4. Sachin R Jhawar1
  1. 1Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA
  2. 2Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA
  3. 3Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA
  1. Correspondence to Dr Sachin R Jhawar; sachin.jhawar{at}


A 63-year-old woman with pathological anatomic/prognostic stage IA ER+/PR+/HER2- multifocal invasive mammary carcinoma with mixed ductal and lobular features of the left breast underwent lumpectomy with sentinel lymph node biopsy. During evaluation of the CT simulation for adjuvant radiation (RT) treatment planning, a liver lesion and splenomegaly were noted. A subsequent MRI abdomen revealed a large, indeterminate splenic lesion with a wide differential and a benign liver cyst. The patient ultimately underwent splenectomy, with pathology consistent with littoral cell angioma, a rare entity associated with several malignancies. At last follow-up, 7 months after completion of RT, she remained cancer free while on anastrazole and was doing well clinically.

  • breast cancer
  • radiotherapy
  • pathology
  • general surgery

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  • Contributors Supervised by SRJ. Patient was under the care of SRJ and KAP. Report was written by AY, SRJ, KAP and DJ.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.