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Rare case of interstitial nephritis in a young adult under IgG therapy
  1. Ana Carolina Figueiredo1,2,
  2. Inês Nunes3,
  3. Emanuel Ferreira1,2 and
  4. Emilia Faria3
  1. 1Nephrology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal
  2. 2Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal
  3. 3Allergy and Clinical Immunology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal
  1. Correspondence to Dr Ana Carolina Figueiredo; carolinarfigueiredo{at}


Immunoglobulin replacement therapy is an important therapeutic approach used in different diseases, such as immunodeficiency diseases. We report a case of a 19-year-old female patient with suspected common variable immunodeficiency who started replacement therapy with IgG. During the follow-up, she developed interstitial nephritis and the subsequent workup excluded other diseases or triggers except IgG therapy.

  • immunological products and vaccines
  • renal system
  • medical management

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  • ACF and IN are joint first authors.

  • Contributors ACF and IN are equally contributing first authors who participated in the patient management and article writing. Both EFe and EFa contributed in patient follow-up and article writing and revision.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.