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Adenomyoepithelioma of the breast: a rare diagnosis complicated by surgical emergency and diagnostic uncertainty
  1. Christopher Michael Ford1,
  2. Hilary Regan1,
  3. Moyna Dwyer2 and
  4. Gaurel Patel3
  1. 1Academic Centre, Milton Keynes University Hospital, Milton Keynes, UK
  2. 2Pathology, Milton Keynes University Hospital, Milton Keynes, UK
  3. 3Breast Care Unit, Milton Keynes University Hospital, Milton Keynes, UK
  1. Correspondence to Mr Christopher Michael Ford; 1704805{at}


A woman in her 80s was referred as an emergency case with a large oedematous and ulcerating lesion of the right breast. There was a 5-month history of increasing breast volume with new onset skin breakdown and discharge. Imaging revealed an extensive heterogeneous mass requiring drainage. No diagnosis was received from multiple biopsies and immediate surgical resection of the breast and axillary sampling was prioritised given the deteriorating patient condition. Postoperative histology identified a biphasic Adenomyoepithelioma of low malignant potential, a rare presentation compounding the complexity of management. The diagnostic uncertainty of this case highlighted the importance of MDT collaboration and the flexibility of current management pathways when dealing with cases requiring urgent surgical intervention. Axillary sampling in the context of unsuccessful preoperative biopsy represented a comprehensive means for assessing the need for further surgical or systemic management in the context of unconfirmed malignancy in a deteriorating patient.

  • breast cancer
  • breast surgery
  • radiology
  • cancer intervention

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  • Contributors Article writing was undertaken by CMF and HR with additional support from GP and MD. Histopathological sample images were provided by MD.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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