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Case Reports: Rare disease
Abdominal Kikuchi-Fujimoto lymphadenopathy: an uncommon presentation of a rare disease
  1. Marco Fiori1,
  2. Paolo Spina2,
  3. Rita Monotti1 and
  4. Igor Salvadé1
  1. 1Internal Medicine, EOC, Bellinzona, Switzerland
  2. 2Cantonal Institute of Pathology, EOC, Bellinzona, Switzerland
  1. Correspondence to Dr Igor Salvadé; igor.salvade{at}eoc.ch

Abstract

A 34-year-old man presented to our hospital with a 5-day history of progressive abdominal pain and fever. A CT scan identified extensive mesenteric lymphadenopathy. Initial diagnostic tests were inconclusive. Abdominal lymph node biopsy showed histiocytic necrotising lymphadenitis, compatible with Kikuchi-Fujimoto disease (KFD). This benign and self-limiting disease generally resolves following supportive treatment. In this case, remission occurred within 3 weeks of initial presentation. KFD is a very uncommon cause of lymphadenopathy, and selective mesenteric involvement is rare. Definitive diagnosis often requires lymph node biopsy. It is important to exclude more common and serious differential diagnoses associated with mesenteric lymphadenopathy, while maintaining a minimally invasive diagnostic approach, before progressing to nodal biopsy.

  • pathology
  • immunology
  • haematology (incl blood transfusion)

https://doi.org/10.1136/bcr-2021-244732

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    Footnotes

    • Contributors MF and IS took care of the patient during hospitalisation. They took part in the preparation of the manuscript. SP analysed the biopsy and prepared the figure. RM helped IS in the supervision of the work.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.