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Case Reports: Rare disease
Subcutaneous panniculitis-like T-cell lymphoma: an unusual cause of right thigh hypertrophy
  1. Mahmoud Husni Ayesh (Haj Yousef)1,
  2. Sohaib M Al-Khatib2,
  3. Ruba A Khasawneh3 and
  4. Laith Rahabneh1
  1. 1Department of Medicine, Jordan University of Science and Technology, Irbid, Jordan
  2. 2Deapertment of Pathology and Microbiology, Jordan University of Science and Technology, Irbid, Jordan
  3. 3Department of Diagnostic Radiology and Nuclear Medicine, Jordan University of Science and Technology, Irbid, Jordan
  1. Correspondence to Dr Mahmoud Husni Ayesh (Haj Yousef); ayeshmahmoud{at}hotmail.com

Abstract

A man in his mid-20s presented with a painless swelling over his right thigh, which had been progressively increasing over 3 years. He underwent an excisional biopsy for the same, which showed reactive lymphadenopathy. Since the last year and a half, he developed a lower abdominal wall swelling with mild redness over it. In addition, over the last few months before presentation to haematology outpatient clinic, he experienced bouts of fever, night sweats, anorexia, weight loss and right inguinal lymphadenopathy. On examination, splenomegaly was identified. In view of the patients’ symptoms, he underwent a positron emission tomography scan, which showed hypermetabolic activity in the subcutaneous tissue sparing the lymph nodes and spleen. A deep skin punch biopsy taken from his right thigh was consistent with the diagnosis of subcutaneous panniculitis-like T-cell lymphoma αβ T-cell phenotype. The patient was treated successfully with oral steroids and on routine follow-up, he is in remission for 5 years.

  • Haematology (drugs and medicines)
  • Dermatology
  • Skin

https://doi.org/10.1136/bcr-2022-253469

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    Footnotes

    • Contributors MHA contributed to the data analysis and manuscript preparation and direct care of the patient. SMA-K contributed to pathology analysis. RAK contributed to the image analyses. LR contributed to collecting of data. All the authors approved the final version of the submitted manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.