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Unexpected case of postnatal pancreatitis: first presentation of autoimmune diabetes
  1. Zi Xi Poo,
  2. Wen Shan Sim and
  3. Lay Kok Tan
  1. Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore
  1. Correspondence to Dr Zi Xi Poo; poo.zi.xi{at}


Gestational diabetes mellitus (GDM) is defined as the first onset of glucose intolerance in pregnancy without prior known diabetes. While it is commonly associated with metabolic risk factors such as obesity and hypertension, a small percentage of women with GDM have underlying autoimmune causes, with presence of islet-cell antibodies resulting in autoimmune-mediated destruction of the pancreas. We present a case of idiopathic postpartum pancreatitis precipitating fulminant diabetic ketoacidosis in a patient with otherwise well-controlled GDM during pregnancy, and subsequent findings of positive anti-glutamic acid decarboxylase antibody. This is the first presentation of autoimmune diabetes diagnosed postnatally in a woman who has no previous medical or family history.

  • Diabetes
  • Pregnancy

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  • Contributors ZXP collected and analysed the patient data, drafted and revised the paper. WSS initiated the design of the paper, analysed the data, drafted and revised the paper. LKT drafted and revised the paper. All authors gave final approval of the version to be published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.