Article Text
Abstract
Pancreatic acinar cell carcinoma is a rare type of pancreatic malignancy, which can be confused with pancreatic neuroendocrine neoplasm. Here, we describe a woman in her 80s who presented with abdominal pain and bilateral lower extremity panniculitis. She underwent surgery for a presumed diagnosis of neuroendocrine tumour with PTEN and PRKAR1A alterations; 19 months, later, a recurrence of her pancreatic malignancy was discovered. The patient underwent repeat resection and this time immunohistochemical staining confirmed the diagnosis of acinar cell carcinoma. Staining for acinar cell carcinoma should be prompted based on clinical suspicion in context of PTEN or PRKAR1A mutation when appropriate.
- surgical oncology
- pancreatic cancer
Statistics from Altmetric.com
Footnotes
Contributors Conception and design: ZY, JGZR, KB, NAT and CH. Acquisition of the data: ZY, JGZR, HB, KB, NAT and CH. Interpretation of the data: ZY, JGZR, KB, NAT and CH. Manuscript draft and revision: ZY, JGZR, HB, KB, NAT and CH. All authors (ZY, JGZR, HB, KB, NAT and CH) have approved the final manuscript and agree to be accountable for this manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.