You are here

Article Text

Article menu
Download PDFPDF
Case Reports: Adverse drug reactions and complications
Chalazion in a patient with multiple myeloma treated with bortezomib
  1. Bipin Ghimire1,
  2. Yuko Hamajima2,
  3. Lorena Carbajal-Carballo3 and
  4. Nwabundo Anusim3
  1. 1Department of Internal Medicine, Beaumont Hospitals, Royal Oak, Michigan, USA
  2. 2Department on Oncology, University of Texas at Austin Dell Seton Medical Center, Austin, Texas, USA
  3. 3Department of Oncology, University of Texas at Austin Dell Medical School, Austin, Texas, USA
  1. Correspondence to Dr Nwabundo Anusim; nwabundo.anusim{at}austin.utexas.edu

Abstract

We present a case of a woman in her early 60s with multiple myeloma who, while undergoing treatment with cyclophosphamide, bortezomib and dexamethasone (CyBorD), noticed a whitish nodular swelling on the eyelid. This occurred after one cycle of CyBorD and on subsequent treatment, it also involved the contralateral eyelid. The lesions were initially managed with conservative measures by applying warm compresses, but the lesions progressively increased in size. CyBorD was discontinued and topical antibiotics and anti-inflammatories were initiated, resulting in a decrease in size of the lesions. On resolution of symptoms, she was rechallenged with CyBorD, and symptoms did not recur. The temporal relationship between bortezomib and the development of chalazion is based on connection and no association has been proven.

  • Eye
  • Haematology (drugs and medicines)

https://doi.org/10.1136/bcr-2022-251077

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors BG and NA contributed to manuscript writing and review. LC-C reviewed the paper. YH took pictures, managed the patient and reviewed the paper.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.