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Hypercalcaemia secondary to acute rhinovirus infection
  1. Hui Jun Guo1,
  2. Abhinav Karan1,
  3. Amy Kiamos1 and
  4. Vishal Jaikaransingh2
  1. 1Internal Medicine, University of Florida College of Medicine—Jacksonville, Jacksonville, Florida, USA
  2. 2Internal Medicine—Nephrology, UF Health Jacksonville, Jacksonville, Florida, USA
  1. Correspondence to Dr Hui Jun Guo; huijun.guo{at}


Hypercalcaemia-induced rhinovirus has only been reported in a single study in children. Here, we report a case of hypercalcaemia in an adult who tested positive for rhinovirus. This patient underwent an extensive evaluation of hypercalcaemia, and it was found to be mediated by an increase in 1,25 hydroxy-vitamin D that could not be attributed to a cause. Their hypercalcaemia responded to standard treatment with intravascular expansion, bisphosphonates and calcitonin. Serum 1,25 OH vitamin D levels returned to normal with recovery from rhinovirus infection.

  • Metabolic disorders
  • Calcium and bone
  • Infectious diseases

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  • Contributors All authors contributed equally to the production of this manuscript. HJG and AKaran contributed to the body of the manuscript. AKiamos and VJ contributed to the review of the manuscript. All authors are in agreement of the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.