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Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH): a little known cause of thoracic lesions
  1. Anne-Marie Ionescu,
  2. Peter Skidmore and
  3. Ghanem Aldik
  1. Respiratory Medicine, Royal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey, UK
  1. Correspondence to Dr Anne-Marie Ionescu; annemarie.ionescu{at}


Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare but important condition to consider when investigating a patient with suspected thoracic malignancy. There is very little known about DIPNECH and it is considered to be a precursor to carcinoid tumour of the lung. This case report aims to increase awareness of this largely unknown and rare condition and to better improve its consideration as a differential diagnosis in patients who remain unresponsive to conventional treatment.

  • Bronchopulmonary Dysplasia
  • Lung cancer (oncology)
  • Pathology

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  • Contributors AI has contributed by writing the majority of the report piece and obtaining the images used in the case report including liaising with the pathology department for the histology images. PS has contributed by obtaining verbal and written consent from the patient presented in the report. He has also contributed to the writing of the report itself. GA has provided overall guidance for the report as well as help editing and help obtaining the images provided in the report itself.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.