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ABPA sans asthma: an entity to remember
  1. Avinash Anil Nair1,
  2. Leena Robinson Vimala2,
  3. Divya Chandran2 and
  4. Richa Gupta1
  1. 1Department of Respiratory Medicine, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
  2. 2Department of Radiology, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
  1. Correspondence to Dr Avinash Anil Nair; avinash444{at}


A male patient in his 20s presented with a cough and a small volume of haemoptysis that lasted a year. He had no other constitutional symptoms and a respiratory examination was suggestive of a consolidation. A chronic infection, such as tuberculosis, was suspected. The routine evaluation showed peripheral eosinophilia with raised serum total IgE. Sputum examination for tuberculosis was negative; hence, a high-resolution CT of the thorax was performed, which revealed bilateral bronchiectasis with high-attenuation mucus plugging. The imaging and blood profiles were in favour of allergic bronchopulmonary aspergillosis, but there was no history suggestive of asthma, and the pulmonary function test was normal. The patient underwent a skin prick test and an allergen-specific IgE test for Aspergillus fumigatus, and both were positive. His bronchoalveolar lavage cultures also grew A. fumigatus, and he responded well to antifungal therapy. This case illustrates the presentation of a rare entity—allergic bronchopulmonary aspergillosis sans asthma.

  • Respiratory medicine
  • Asthma
  • Respiratory system
  • Allergy, asthma
  • TB and other respiratory infections

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  • Contributors AAN—diagnosis, manuscript preparation and editing, and final draft review. DC—manuscript writing and editing. LRV—radiological diagnosis, images and legends. RG—manuscript draft revision and final draft corrections.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.