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Concomitant giant purely intradiploic cavernous haemangioma and multifocal neurotoxoplasmosis
  1. Roberta Costanzo1,
  2. Gianluca Scalia2,
  3. Domenico Gerardo Iacopino1 and
  4. Giovanni Nicoletti2
  1. 1Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, University of Palermo, Palermo, Italy
  2. 2Department of Neurosurgery, Garibaldi Hospital, Catania, Italy
  1. Correspondence to Dr Gianluca Scalia; gianluca.scalia{at}


Purely calvarial or intradiploic cavernous haemangiomas (PICHs) are rare benign tumours accounting for 0.2% of all bone tumours and 10% of benign skull tumours. They are generally small, slow-growing and asymptomatic lesions. Here the authors described an immunocompromised patient with concomitant giant intradiploic ossified globular cavernous angioma and multifocal neurotoxoplasmosis that underwent a combined approach to treat both lesions with an en-bloc resection of the right parietal intradiploic lesion and biopsy of the left occipital subcortical lesion.

Indeed, it is essential to exclude the presence of metastases by making a timely differential diagnosis. En-bloc surgical resection of purely intradiploic ossified cavernous angioma is the gold standard treatment and the prognosis after a complete excision is usually excellent with rarer recurrence rate.

  • neurosurgery
  • surgery
  • infection control in hospital
  • neurooncology

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  • Contributors Study conceptualisation was done by GS and RC. GS was responsible for methodology. Resources were obtained by GS and RC. Data curation was done by RC. Writing original draft preparation was done by RC and GS. Review and editing were done by GS and RC. Supervision was done by DGI and GN. All authors have read and agreed to the published version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.